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(Senior) Scientist, MS

EPM Scientific
locationLos Angeles, CA, USA
PublishedPublished: 6/14/2022
Science
Full Time

Job Description

Job Description

(Senior) Scientist, MS

Overview:
A cutting-edge biotech startup is seeking a Mass Spectrometry Scientist to lead analytical efforts across a diverse pipeline of therapeutics. This is a high-impact role for someone passionate about applying advanced analytical techniques to solve complex challenges in therapeutic development.

Key Responsibilities:

  • Perform top-down proteomics for intact mass confirmation and drug-to-antibody ratio (DAR) assessments
  • Conduct bottom-up peptide mapping in collaboration with chemists and protein engineers
  • Analyze in vivo plasma and tissue samples via LC-MS/MS for PK quantification
  • Develop and standardize data processing and reporting pipelines
  • Serve as a technical liaison with external CROs and instrumentation partners
  • Contribute to the build-out of internal mass spec capabilities, including equipment selection and SOP development
  • Collaborate cross-functionally with chemistry, biology, and CMC teams

Qualifications:

  • M.S. or Ph.D. in Analytical Chemistry, Biochemistry, Pharmaceutical Sciences, or related field
  • 2-5 years of experience in mass spectrometry, preferably in biologics, ADCs, or oligonucleotides
  • Hands-on experience with LC-MS/MS, intact protein analysis, peptide mapping, and PK quantification
  • Familiarity with conjugation chemistry and CRO management
  • Strong data analysis skills using tools like Xcalibur, MassLynx, Skyline, or BioPharma Finder

Preferred Experience:

  • Oligonucleotide/peptide mass spec in biological matrices
  • Bioconjugation, protein engineering, or organic synthesis
  • Early-stage CMC analytical development and regulatory awareness
  • Comfort working in a startup environment with evolving infrastructure

What's Offered:

  • Opportunity to shape analytical strategy in a fast-paced, platform-driven environment
  • Competitive compensation, equity, and benefits
  • A collaborative team culture rooted in scientific rigor and innovation
  • Modern R&D facility equipped for high-throughput discovery and translational biology

Company DescriptionA top 10 pharmaceutical company with an immense amount of growth after releasing their at home COVID diagnostic tests is looking to bring on 200+ Quality Individuals through a massive hiring campaign. In their search for Quality Specialists, the organization is looking for individuals who will be responsible for reviewing and actioning customer complaints, as well as investigation into said complaints.
Job Responsibilities:
•\tConducting Post Market Activities and Post Market Surveillance
•\tManaging Customer and Product Complaint Investigation programs
Education and Experience:
•\t1 YR. of experience in a technical role in the medical device/pharma/biotech industry
•\tBachelor's degree
•\tComputer proficiency

Company Description

A top 10 pharmaceutical company with an immense amount of growth after releasing their at home COVID diagnostic tests is looking to bring on 200+ Quality Individuals through a massive hiring campaign. In their search for Quality Specialists, the organization is looking for individuals who will be responsible for reviewing and actioning customer complaints, as well as investigation into said complaints.\r\nJob Responsibilities:\r\n•\tConducting Post Market Activities and Post Market Surveillance\r\n•\tManaging Customer and Product Complaint Investigation programs\r\nEducation and Experience:\r\n•\t1 YR. of experience in a technical role in the medical device/pharma/biotech industry\r\n•\tBachelor's degree\r\n•\tComputer proficiency

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