Synthetic Organic Chemist

Job Description

Job DescriptionOur client is seeking a Synthetic Organic Chemist to support its small-molecule drug discovery programs. This position plays a critical role in designing and synthesizing high-quality compounds to accelerate structure–activity relationship (SAR) studies for oncology targets. Working closely with internal teams and external CROs, this role is central to advancing early discovery projects in a collaborative and innovation-driven environment.

Key Responsibilities

• Design and execute efficient, scalable synthetic routes for small-molecule analogs (milligram to multi-gram scale).
• Support SAR campaigns through parallel synthesis and application of modern synthetic methods.
• Troubleshoot complex synthetic challenges independently and creatively.
• Collaborate with internal teams and CRO partners to coordinate and optimize synthetic efforts.
• Maintain detailed, compliant electronic lab notebooks for IP and regulatory documentation.

Qualifications

• M.S. or Ph.D. in Organic Chemistry or related field with 4+ years of relevant industry experience.
• Proven expertise in modern synthetic organic chemistry and multi-step synthesis strategies.
• Experience in purification and structural characterization techniques (NMR, LC-MS, etc.)
• Experience with milligram to decagram-scale synthesis of intermediates and final compounds.
• Strong ability to deliver analog libraries and manage CRO relationships.
• Excellent documentation habits and communication skills; collaborative and detail-oriented.

#IND-SPG

Estimated Min Rate: $65.00
Estimated Max Rate: $80.00

What’s In It for You?
We welcome you to be a part of the largest and legendary global staffing companies to meet your career aspirations. Yoh’s network of client companies has been employing professionals like you for over 65 years in the U.S., UK and Canada. Join Yoh’s extensive talent community that will provide you with access to Yoh’s vast network of opportunities and gain access to this exclusive opportunity available to you. Benefit eligibility is in accordance with applicable laws and client requirements. Benefits include:

• Medical, Prescription, Dental & Vision Benefits (for employees working 20+ hours per week)
• Health Savings Account (HSA) (for employees working 20+ hours per week)
• Life & Disability Insurance (for employees working 20+ hours per week)
• MetLife Voluntary Benefits
• Employee Assistance Program (EAP)
• 401K Retirement Savings Plan
• Direct Deposit & weekly epayroll
• Referral Bonus Programs
• Certification and training opportunities

Note: Any pay ranges displayed are estimations. Actual pay is determined by an applicant's experience, technical expertise, and other qualifications as listed in the job description. All qualified applicants are welcome to apply.

Yoh, a Day & Zimmermann company, is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or status as a protected veteran.

Visit https://www.yoh.com/applicants-with-disabilities to contact us if you are an individual with a disability and require accommodation in the application process.

For California applicants, qualified applicants with arrest or conviction records will be considered for employment in accordance with the Los Angeles County Fair Chance Ordinance for Employers and the California Fair Chance Act. All of the material job duties described in this posting are job duties for which a criminal history may have a direct, adverse, and negative relationship potentially resulting in the withdrawal of a conditional offer of employment.

By applying and submitting your resume, you authorize Yoh to review and reformat your resume to meet Yoh’s hiring clients’ preferences. To learn more about Yoh’s privacy practices, please see our Candidate Privacy Notice: https://www.yoh.com/privacy-noticeCompany DescriptionFounded in 1940, Yoh operates from 75 locations throughout North America and is headquartered in Philadelphia, PA. Yoh was the nation’s first technology staffing firm. As a business unit of Day & Zimmermann, Yoh has a flourishing global footprint, as our parent company operates from more than 150 worldwide locations.
Company Website: https://www.yoh.com/

Company Description

Founded in 1940, Yoh operates from 75 locations throughout North America and is headquartered in Philadelphia, PA. Yoh was the nation’s first technology staffing firm. As a business unit of Day & Zimmermann, Yoh has a flourishing global footprint, as our parent company operates from more than 150 worldwide locations.\r\nCompany Website: https://www.yoh.com/